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General ScienceMediumAsked in: UPSC Civil Services · CSE Prelims 2019, GS Paper I

Which of the following are the reasons for the occurrence of multi-drug resistance in microbial pathogens in India? 1. Genetic predisposition of some people 2. Taking incorrect doses of antibiotics to cure diseases 3. Using antibiotics in livestock farming 4. Multiple chronic diseases in some people Select the correct answer using the code given below.

  1. A.1 and 2
  2. B.2 and 3 only
  3. C.1, 3 and 4
  4. D.2, 3 and 4

Correct answer

B. 2 and 3 only

Explanation

The correct answer is B, 2 and 3 only. Drug resistance grows in microbes when antibiotics are misused, and both wrong doses and farm use of antibiotics are forms of misuse. Every time bacteria meet an antibiotic in a dose too low or for too short a time, the weakest die and the toughest survive and multiply, so resistant strains spread. Self-medication, stopping a course midway and buying antibiotics without a prescription all add to this. Antibiotics fed to poultry and cattle, often to speed growth rather than to treat disease, expose huge numbers of bacteria to these drugs, and the resistant ones reach people through food, water and soil. Statement 1 is wrong because resistance is a change in the microbe's genes, not in the patient's. Statement 4 is wrong because chronic illness makes a person more likely to catch infections, but it does not itself make microbes resistant. Option A is wrong because it includes statement 1. Option C is wrong because it includes statements 1 and 4 and drops 2. Option D is wrong because it includes statement 4. Exam tip: antimicrobial resistance comes from antibiotic misuse in people and in animals.

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Q2.General ScienceAsked in: CDS · CDS-I 2019, GKEasy

Which one of the following statements is correct?

  1. A.Urea is produced in liver.
  2. B.Urea is produced in blood.
  3. C.Urea is produced from digestion of starch.
  4. D.Urea is produced in lung and kidney.
Show answer
Correct answer: A. Urea is produced in liver.

Liver cells turn the toxic ammonia released from the breakdown of amino acids into urea through the ornithine cycle, also called the urea cycle.

Q3.General ScienceAsked in: CDS · CDS-I 2019, GKMedium

Which one of the following is the correct sequence of passage of light in a compound microscope?

  1. A.Condenser-Objective lens-Eyepiece-Body tube
  2. B.Objective lens-Condenser-Body tube-Eyepiece
  3. C.Condenser-Objective lens-Body tube-Eyepiece
  4. D.Eyepiece-Objective lens-Body tube-Mirror
Show answer
Correct answer: C. Condenser-Objective lens-Body tube-Eyepiece

Light passes through the condenser to the specimen, is picked up by the objective lens, travels up the body tube and reaches the eye through the eyepiece.

Q4.General ScienceAsked in: CDS · CDS-I 2019, GKEasy

Which one of the following statements regarding haemoglobin is correct?

  1. A.Haemoglobin present in RBC can carry only oxygen but not carbon dioxide.
  2. B.Haemoglobin of RBC can carry both oxygen and carbon dioxide.
  3. C.Haemoglobin of RBC can carry only carbon dioxide.
  4. D.Haemoglobin is only used for blood clotting and not for carrying gases.
Show answer
Correct answer: B. Haemoglobin of RBC can carry both oxygen and carbon dioxide.

It binds oxygen at its iron-containing haem groups and carries some carbon dioxide on its protein chains. Each haemoglobin molecule has four polypeptide chains and four haem groups, and each haem iron can hold one oxygen molecule, forming oxyhaemoglobin in the lungs.

Q5.General ScienceAsked in: CDS · CDS-I 2019, GKEasy

Which one of the following statements regarding histone proteins is correct?

  1. A.Histones are proteins that are present in mitochondrial membrane.
  2. B.Histones are proteins that are present in nucleus in association with DNA.
  3. C.Histones are proteins associated with lipids in the cytosol.
  4. D.Histones are proteins associated with carbohydrates in the cytosol.
Show answer
Correct answer: B. Histones are proteins that are present in nucleus in association with DNA.

They are the proteins around which DNA winds to form chromatin in the nucleus of eukaryotic cells. Histones are small basic proteins, rich in the positively charged amino acids lysine and arginine, which attract the negatively charged phosphate groups of DNA.