Bacille Calmette-Guerin (BCG) is a vaccine for ______.
- A.typhoid
- B.tuberculosis (TB)
- C.mumps
- D.plague
Correct answer
Explanation
The correct answer is B, tuberculosis (TB). The BCG vaccine takes its name from Albert Calmette and Camille Guerin, the two French scientists who developed it from a weakened strain of Mycobacterium bovis. In India it is given as a single dose soon after birth under the Universal Immunisation Programme, and it protects infants mainly from the severe forms of the disease, such as tuberculous meningitis and miliary tuberculosis. Tuberculosis itself is caused by the bacterium Mycobacterium tuberculosis, identified by Robert Koch in 1882, and it spreads through droplets when a patient coughs. Option A is wrong because typhoid, caused by Salmonella typhi, has its own conjugate vaccine. Option C is wrong because mumps is a viral disease covered by the MMR vaccine along with measles and rubella. Option D is wrong because plague, caused by Yersinia pestis and carried by rat fleas, needs a different vaccine. Exam tip: BCG at birth for TB, and World TB Day falls on 24 March.
Practice Questions
View allThe fact that the planets move around the Sun, not in circles but in ellipses, was first demonstrated by
- A.Galileo
- B.Martin Luther
- C.Johannes Kepler
- D.Copernicus
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In 1609 Kepler showed that the planets move around the Sun in elliptical orbits, with the Sun at one focus of the ellipse.
Read the full explanation →Which one of the following statements is correct?
- A.Urea is produced in liver.
- B.Urea is produced in blood.
- C.Urea is produced from digestion of starch.
- D.Urea is produced in lung and kidney.
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Liver cells turn the toxic ammonia released from the breakdown of amino acids into urea through the ornithine cycle, also called the urea cycle.
Read the full explanation →Which one of the following is the correct sequence of passage of light in a compound microscope?
- A.Condenser-Objective lens-Eyepiece-Body tube
- B.Objective lens-Condenser-Body tube-Eyepiece
- C.Condenser-Objective lens-Body tube-Eyepiece
- D.Eyepiece-Objective lens-Body tube-Mirror
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Light passes through the condenser to the specimen, is picked up by the objective lens, travels up the body tube and reaches the eye through the eyepiece.
Read the full explanation →Which one of the following statements regarding haemoglobin is correct?
- A.Haemoglobin present in RBC can carry only oxygen but not carbon dioxide.
- B.Haemoglobin of RBC can carry both oxygen and carbon dioxide.
- C.Haemoglobin of RBC can carry only carbon dioxide.
- D.Haemoglobin is only used for blood clotting and not for carrying gases.
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It binds oxygen at its iron-containing haem groups and carries some carbon dioxide on its protein chains. Each haemoglobin molecule has four polypeptide chains and four haem groups, and each haem iron can hold one oxygen molecule, forming oxyhaemoglobin in the lungs.
Read the full explanation →Which one of the following statements regarding histone proteins is correct?
- A.Histones are proteins that are present in mitochondrial membrane.
- B.Histones are proteins that are present in nucleus in association with DNA.
- C.Histones are proteins associated with lipids in the cytosol.
- D.Histones are proteins associated with carbohydrates in the cytosol.
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They are the proteins around which DNA winds to form chromatin in the nucleus of eukaryotic cells. Histones are small basic proteins, rich in the positively charged amino acids lysine and arginine, which attract the negatively charged phosphate groups of DNA.
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