NPPA Caps Trade Margins on 137 Anti-Cancer Drugs
NPPA has capped trade margins on 137 anti-cancer drugs, so 1031 formulations turn cheaper from 9 November 2026, saving patients Rs 3,502.31 crore a year.

Why in News
On 7 November 2026 the Department of Pharmaceuticals said NPPA’s cap on trade margins for 137 anti-cancer drugs takes effect from 9 November 2026, cutting the price of 1031 formulations and saving buyers an estimated Rs 3,502.31 crore a year.
The National Pharmaceutical Pricing Authority (NPPA) has placed a ceiling on the trade margin that may be charged on 137 anti-cancer medicines, and the cheaper rates that follow will apply from 9 November 2026.
Who took the decision
NPPA functions under the Department of Pharmaceuticals in the Ministry of Chemicals and Fertilizers. It acted on the advice of an expert committee set up by the Directorate General of Health Services (DGHS), a body under the Ministry of Health and Family Welfare. The order carries notification number SO 5690 (E), is dated 17 October 2026 and stays in force until the authority says otherwise. The measure is known as Trade Margin Rationalisation (TMR) and covers anti-cancer medicines that lie outside the scheduled list, where prices were not capped earlier. The margin a seller may add is held at 30 per cent.
How far the prices fall
So far 76 drug makers have filed fresh retail prices for 1225 anti-cancer formulations, which between them cover 121 drugs. A lower price has been reported for 1031 of those formulations. Roughly 600 brands become cheaper by more than half, and the steepest single cut runs to 96.45 per cent. Of the 137 drugs on the list, ten to fifteen are not yet sold in India; the margin cap will apply to them as well on the day they reach the market.
What patients save
Once the revised rates begin, the yearly saving for buyers is put at Rs 3,502.31 crore. Several widely used brands of bevacizumab, abiraterone, palbociclib and pertuzumab now sell for a fraction of their earlier price. The medicines brought under the cap treat the commonest cancers.
| Bevacizumab 100 mg injection | Lung, colon, ovary and cervical cancer |
| Denosumab 60 mg injection | Breast and prostate cancer; prevents bone loss |
| Abiraterone acetate 250 mg tablet | Prostate cancer |
| Azacitidine 100 mg injection | Blood cancer |
| Fulvestrant 250 mg injection | Breast cancer |
| Palbociclib 125 mg capsule | Breast cancer |
| Pemetrexed 500 mg vial | Lung cancer |
| Pertuzumab 420 mg injection | Breast cancer |
| Pegfilgrastim 6 mg injection | Prevents neutropenia in cancer patients |
How the rates will be policed
Every retailer, dealer, hospital and institution must put up the revised price list of anti-cancer medicines on its premises and on its website. State Drug Controllers are to watch whether makers, dealers, hospitals and medical institutions keep to the new ceiling. A patient can look up the price that ought to be charged through the Pharma Sahi Daam mobile application or on the NPPA website, and report overcharging to the authority. Companies may still take the yearly increase that Paragraph 20(1) of the Drugs (Prices Control) Order, 2013 permits, so long as they stay within the permitted margin. The government describes the step as part of a continuing effort to make cancer treatment affordable and within reach.
Important Facts
| Regulator | National Pharmaceutical Pricing Authority (NPPA) |
|---|---|
| Parent ministry | Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers |
| Measure | Trade Margin Rationalisation (TMR) on 137 non-scheduled anti-cancer drugs |
| Effective from | 9 November 2026 |
| Notification | SO 5690 (E) dated 17 October 2026 |
| Maximum trade margin | 30 per cent |
| Prices reported | 1225 formulations covering 121 drugs, by 76 companies |
| Formulations made cheaper | 1031, of which about 600 brands fall by more than half |
| Highest reduction | 96.45 per cent |
| Estimated annual saving | Rs 3,502.31 crore |
| Expert committee set up by | Directorate General of Health Services (DGHS), Ministry of Health and Family Welfare |
| Where to check prices | Pharma Sahi Daam mobile app and the NPPA website |
Exam Point of View
Remember the regulator (NPPA), its department (Pharmaceuticals, under the Ministry of Chemicals and Fertilizers), the measure (Trade Margin Rationalisation), the number of drugs (137), the date of effect (9 November 2026), the margin ceiling (30 per cent), the highest cut (96.45 per cent), the annual saving (Rs 3,502.31 crore) and the app for checking prices (Pharma Sahi Daam).
Practice Questions
From which date do the revised prices of the 137 anti-cancer drugs take effect?
- A.1 November 2026
- B.9 November 2026
- C.17 October 2026
- D.1 January 2027
Show answer
NPPA capped the trade margin on the maximum retail price of 137 anti-cancer drugs, and the lower prices that follow from that cap begin on that day.
Read the full explanation →Which authority has capped the trade margins on non-scheduled anti-cancer medicines?
- A.Central Drugs Standard Control Organisation
- B.National Pharmaceutical Pricing Authority
- C.Drug Controller General of India
- D.Directorate General of Health Services
Show answer
The correct answer is the National Pharmaceutical Pricing Authority (NPPA), which works under the Department of Pharmaceuticals in the Ministry of Chemicals and Fertilizers and fixed the ceiling on trade margins for 137 anti-cancer drugs.
Read the full explanation →What is the estimated annual saving to consumers from the revised anti-cancer drug prices?
- A.Rs 1,250 crore
- B.Rs 2,340 crore
- C.Rs 3,502.31 crore
- D.Rs 7,800 crore
Show answer
The figure follows from price cuts reported in 1031 anti-cancer formulations, out of 1225 for which 76 companies filed revised prices, covering 121 drugs in all.
Read the full explanation →What is the maximum permissible trade margin on these anti-cancer medicines?
- A.10 per cent
- B.20 per cent
- C.30 per cent
- D.50 per cent
Show answer
That is the ceiling on the trade margin which sellers of these anti-cancer medicines must observe, and a company may take the annual price increase allowed by Paragraph 20(1) of the Drugs (Prices Control) Order, 2013 only while it continues to respect that limit.
Read the full explanation →Frequently Asked Questions
From which date do the revised prices of anti-cancer medicines apply?
From 9 November 2026. NPPA capped trade margins on 137 anti-cancer drugs, 1031 formulations have been reported cheaper, and the estimated yearly saving for buyers is Rs 3,502.31 crore.
What is the maximum trade margin allowed on these anti-cancer medicines?
30 per cent. Notification SO 5690 (E) dated 17 October 2026 fixes that ceiling. Companies may still claim the annual increase allowed under Paragraph 20(1) of the Drugs (Prices Control) Order, 2013 while staying within it.
Where can a patient check the correct price of an anti-cancer medicine?
On the Pharma Sahi Daam mobile application or the NPPA website. Retailers, dealers, hospitals and institutions must also display the revised price list, and State Drug Controllers monitor whether they comply.
Sources
- https://www.pib.gov.in/PressReleasePage.aspx?PRID=2333949 (opens in a new tab) — Press Information Bureau
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