In the double-helix structure of human DNA, base Adenine forms two hydrogen bonds with which of the following bases to form a base-pair?
- A.Guanine
- B.Cytosine
- C.Thymine
- D.Histone
Correct answer
Explanation
The correct answer is C, Thymine. In DNA, adenine always pairs with thymine through two hydrogen bonds, and guanine pairs with cytosine through three. This is called complementary base pairing, and it is why one strand of DNA can be used to copy the other. The double-helix model was proposed by James Watson and Francis Crick in 1953, using X-ray images made by Rosalind Franklin. Adenine and guanine are purines with two rings, while thymine and cytosine are pyrimidines with one ring, so each pair has the same width and the helix stays even. In RNA, thymine is replaced by uracil. Option A is wrong because guanine is a purine like adenine and pairs with cytosine. Option B is wrong because cytosine pairs with guanine through three hydrogen bonds. Option D is wrong because histone is a protein around which DNA is wound in chromosomes; it is not a base at all. Exam tip: A pairs with T by two bonds, G with C by three; RNA has U in place of T.
Practice Questions
View allThe fact that the planets move around the Sun, not in circles but in ellipses, was first demonstrated by
- A.Galileo
- B.Martin Luther
- C.Johannes Kepler
- D.Copernicus
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In 1609 Kepler showed that the planets move around the Sun in elliptical orbits, with the Sun at one focus of the ellipse.
Read the full explanation →Which one of the following statements is correct?
- A.Urea is produced in liver.
- B.Urea is produced in blood.
- C.Urea is produced from digestion of starch.
- D.Urea is produced in lung and kidney.
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Liver cells turn the toxic ammonia released from the breakdown of amino acids into urea through the ornithine cycle, also called the urea cycle.
Read the full explanation →Which one of the following is the correct sequence of passage of light in a compound microscope?
- A.Condenser-Objective lens-Eyepiece-Body tube
- B.Objective lens-Condenser-Body tube-Eyepiece
- C.Condenser-Objective lens-Body tube-Eyepiece
- D.Eyepiece-Objective lens-Body tube-Mirror
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Light passes through the condenser to the specimen, is picked up by the objective lens, travels up the body tube and reaches the eye through the eyepiece.
Read the full explanation →Which one of the following statements regarding haemoglobin is correct?
- A.Haemoglobin present in RBC can carry only oxygen but not carbon dioxide.
- B.Haemoglobin of RBC can carry both oxygen and carbon dioxide.
- C.Haemoglobin of RBC can carry only carbon dioxide.
- D.Haemoglobin is only used for blood clotting and not for carrying gases.
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It binds oxygen at its iron-containing haem groups and carries some carbon dioxide on its protein chains. Each haemoglobin molecule has four polypeptide chains and four haem groups, and each haem iron can hold one oxygen molecule, forming oxyhaemoglobin in the lungs.
Read the full explanation →Which one of the following statements regarding histone proteins is correct?
- A.Histones are proteins that are present in mitochondrial membrane.
- B.Histones are proteins that are present in nucleus in association with DNA.
- C.Histones are proteins associated with lipids in the cytosol.
- D.Histones are proteins associated with carbohydrates in the cytosol.
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They are the proteins around which DNA winds to form chromatin in the nucleus of eukaryotic cells. Histones are small basic proteins, rich in the positively charged amino acids lysine and arginine, which attract the negatively charged phosphate groups of DNA.
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